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Q&A: Updated AGA Guidance on Managing Post-IPAA Pouchitis

A new American Gastroenterological Association practice guideline provides strategies to reduce high rates of pouchitis after ileal pouch-anal anastomosis. Pouchitis is the most common complication...

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Maximizing Diagnostic Yield & Safety of Transbronchial Lung Cryobiopsy

Several modifiable factors impacted the safety and diagnostic yield of lung cryobiopsy for patients with suspected interstitial lung diseases. Patient characteristics and modifiable procedural factors...

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Perianal Fistual Prior To Crohn’s Disease Diagnosis Impacts Multiple Outcomes

Longer time to Crohn’s disease diagnosis occurs among patients who have a perianal fistula as a manifesting sign and is associated with poorer outcomes. Prolonged time to diagnosis among patients with...

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#VisualAbstract: Lu AG09222, a Monoclonal Antibody Targeting Pituitary...

Click here to read this study in NEJM.  ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about...

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Determinants of Dupilumab Efficacy in Atopic Dermatitis

The following is a summary of “Factors Associated with Dupilumab Response in Atopic Dermatitis: A Systematic Review and Meta-analysis,” published in the September 2024 issue of Allergy and Immunology...

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Evaluating the Specificity of Diagnostic Criteria for Mast Cell Activation...

The following is a summary of “Clustering of clinical symptoms using large language models reveals low diagnostic specificity of proposed alternatives to consensus mast cell activation syndrome...

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Outcomes of Salvage Treatments for Recurrent Prostate Cancer

The following is a summary of “Salvage local treatment for recurrent prostate cancer after focal therapy: A systematic review and meta-analysis,” published in the September 2024 issue of Urology by...

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Ponsegromab for the Treatment of Cancer Cachexia

1. Ponsegromab at increasing doses resulted in a mean increase in body weight compared to placebo; 1.22 kg (2.21%) in the 100-mg group, 1.92 kg (2.99%) in the 200-mg group, and 2.81 kg (5.46) in the...

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Datopotamab deruxtecan may be a novel improvement for inoperable breast cancer

1. Compared to chemotherapy, patients with inoperable hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer receiving the antibody-drug conjugate (ADC)...

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Role of Serial mpMRI and PSA Increase in Upgrading PIRADS Lesions

The following is a summary of “Natural history of PIRADS-2 lesions on serial multiparametric magnetic resonance imaging: Real-life data from an Academic Center,” published in the September 2024 issue...

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Tips for Helping Patients Achieve Restorative Sleep

I introduced some of the ‘homework assignments’ that I prescribe to patients as I support their journey to health, happiness, and understanding of the “good life” in previous columns. These assignments...

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How North Carolina Made Its Hospitals Do Something About Medical Debt

North Carolina officials had been quietly laboring for months on an ambitious plan to tackle the state’s mammoth medical debt problem when Gov. Roy Cooper stepped before cameras in July to announce the...

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She Was Accused of Murder After Losing Her Pregnancy. SC Woman Now Tells Her...

ORANGEBURG, S.C. — Amari Marsh had just finished her junior year at South Carolina State University in May 2023 when she received a text message from a law enforcement officer. “Sorry it has taken this...

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Florida’s New Covid Booster Guidance Is Straight-Up Misinformation

In what has become a pattern of spreading vaccine misinformation, the Florida health department is telling older Floridians and others at highest risk from covid-19 to avoid most booster shots, saying...

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Across North Carolina, Medical Debt Exacts a Heavy Toll

On March 30, 2019, a swerving car upended Tom Burke’s life. Severely injured after the crash, Burke was airlifted from the Fort Liberty U.S. Army base in North Carolina to UNC Medical Center, in Chapel...

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High Prevalence of HPV Types and Vaccine Gaps in Population Screening

The following is a summary of “Population-based age- and type-specific prevalence of human papillomavirus among non-vaccinated women aged 30 years and above in Germany,” published in the September 2024...

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Clinical Benefits of EXOPULSE Mollii Suit in Fibromyalgia Treatment

The following is a summary of “Effect of the EXOPULSE Mollii Suit on pain and fibromyalgia-related symptoms—A randomized sham-controlled crossover trial,” published in the September 2024 issue of Pain...

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Comparison of Repeated Prostaglandin vs. CRB for Unfavorable Cervix at Term

The following is a summary of “Dinoprostone vaginal insert compared to cervical ripening balloon as second line of cervical ripening after first dinoprostone insert,” published in the August 2024 issue...

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Nuclear Trafficking of Membrane Androgen Receptor and its Therapeutic Potential

The following is a summary of “Nuclear translocation of the membrane oxoeicosanoid/androgen receptor, OXER1: possible mechanisms involved,” published in the September 2024 issue of Endocrinology by...

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Evaluation of Patients with Pancreatic Cancer for Radiation Response in...

The following is a summary of “Radiation response assessment of organoids derived from patients with pancreatic cancer,” published in the September 2024 issue of Oncology by Goor et al. The...

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