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Immunotherapy Outcomes in Urological Malignancies Affected by Body Composition

The following is a summary of “Impact of baseline body composition on prognostic outcomes in urological malignancies treated with immunotherapy: a pooled analysis of 10 retrospective studies,”...

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Study Finds Decreased Vitamin K in Patients With Psoriasis

Vitamin K has been shown to promote would contraction and reduce the time it takes for skin to heal, but no previous studies have assessed vitamin K status in patients with psoriasis, a disease...

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Emotional Toll of Psoriasis Affects Quality of Life

Half of patients with moderate psoriasis in a small study had Hamilton Depression Rating Scale (HAM-D) scores indicating mild depression, researchers reported in BRAIN: Broad Research in Artificial...

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Study Confirms Phenotypic Variability in Onset, Legal Blindness in...

A retrospective cohort study confirmed high phenotypic variability in disease onset and age at which legal blindness is reached in patients with PRPF31-associated Retinitis pigmentosa (RP). The study...

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Usher Syndrome Due to MYO7A Mutations Has Implications for Gene Therapy

A multicentric longitudinal prospective study of the natural history of retinitis pigmentosa due to MYO7A gene variants has demonstrated the key role of fundus autofluorescence patterns in the staging...

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Few With T2D Receive Guideline-Recommended CKD Screening

Fewer than one-quarter of patients with type 2 diabetes (T2D) receive recommended chronic kidney disease (CKD) screening, according to a study in JAMA Network Open. A team of researchers conducted a...

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Medical Assistant Health Coaching Enhances Care

A recent cluster randomized controlled trial compared medical assistant health coaching (MAC) to usual care in 600 adults with T2D at two diverse primary care settings: a federally qualified health...

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Most Americans Would Welcome Hospital Care at Home, Survey Shows

According to research published online in the Journal of the American Medical Association, many Americans like the idea of receiving hospital-level care at home, believing they would recover from their...

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More Women Than Men Experience Non-physical Violence in Healthcare Workforce

Women in the healthcare workforce are more likely to experience verbal abuse, sexual harassment, and bullying, while men are more likely to experience physical violence, according to a study in PLOS...

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Comorbidities, Cardiovascular Burden Already Elevated in Early PsA

Even in early disease stages, patients with PsA already have greater multimorbidity and cardiovascular burden than sex- and age-matched controls, according to study findings published in Arthritis Care...

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Assessing Patient-Reported Outcomes in PsA

Clinicians should consider comorbidities when assessing patient-reported outcomes in patients with PsA, according to a study published in Rheumatology International. In 267 adults with PsA, half had...

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Half of Surgeons Exhibit Burnout Symptoms

The effects of physician burnout extend beyond the individual to potentially impact quality of care, patient safety, and healthcare efficiency. Researchers used a 2019 survey of physicians in Saxony,...

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Rates of Gender-Affirming Surgery Examined in Cisgender Males, Gender-Diverse

For adults and minors, most breast reductions performed on cisgender males, transgender, and gender-diverse (TGD) people are performed on cisgender males, according to a research letter published in...

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Prolonged β-Lactam Antibiotic Infusions Aid Sepsis and Septic Shock Outcomes

Among adults in the intensive care unit with sepsis or septic shock, the use of prolonged β-lactam antibiotic infusions is associated with a lower risk of 90-day mortality compared with intermittent...

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Subcutaneous Infusion of Levodopa-Carbidopa Beneficial for Parkinson Disease

Subcutaneous infusion of ND0612 (a levodopa-carbidopa solution) increases on time without troublesome dyskinesia among patients with Parkinson disease, according to a study published in The Lancet...

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COVID-19 vaccination and infection not associated with increased risk of...

1. In a cohort of infants born to mothers during the COVID-19 pandemic, neither vaccination nor infection with COVID-19 led to increased risk of any congenital anomaly.  Evidence Rating Level: 1...

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#VisualAbstract: Irinotecan and Temozolomide Plus Dasatinib and Rapamycin...

Click here to read this study in Lancet Oncology.  ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire...

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Emergency departments likely overprescribing opioids for acute pain

1. In this cohort study, majority of the participants did not use all of the opioids prescribed to them in the emergency department (ED) implicating that doctors working in the ED can lower the number...

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Survivorship of total knee arthroplasty in poliomyelitis patients: long-term...

The survival of total knee arthroplasty (TKA) in patients with poliomyelitis remains a debated topic due to the high recurrence of postoperative genu recurvatum. This study aims to report the long-term...

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Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains...

Intestinal epithelial cells line the luminal surface to establish the intestinal barrier, where the cells play essential roles in the digestion of food, absorption of nutrients and water, protection...

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