Development of a deep-learning model tailored for HER2 detection in breast...
Over 50% of breast cancer cases are “Human epidermal growth factor receptor 2 (HER2) low breast cancer (BC)”, characterized by HER2 immunohistochemistry (IHC) scores of 1+ or 2+ alongside no...
View ArticleCD11b maintains West Nile virus replication through modulation of immune...
West Nile virus (WNV) is a rapidly spreading mosquito-borne virus accounted for neuroinvasive diseases. An insight into WNV-host factors interaction is necessary for development of therapeutic...
View ArticleEvaluation of pathological response to neoadjuvant chemotherapy in locally...
Neoadjuvant chemotherapy (NACT) is a viable therapeutic option for women diagnosed locally advanced cervical cancer (LACC). However, the factors influencing pathological response are still...
View ArticlePHF6 suppresses self-renewal of leukemic stem cells in AML.
Acute myeloid leukemia is characterized by uncontrolled proliferation of self-renewing myeloid progenitors accompanied by a differentiation arrest. PHF6 is a chromatin-binding protein mutated in...
View ArticleEGFR mutations induce the suppression of CD8 T cell and anti-PD-1 resistance...
Non-small cell lung cancer (NSCLC) patients with EGFR mutations exhibit an unfavorable response to immune checkpoint inhibitor (ICI) monotherapy, and their tumor microenvironment (TME) is usually...
View ArticleImaging-based body fat distribution and diabetic retinopathy in general US...
Limited studies have investigated the correlation between fat distribution and the risk of diabetic retinopathy (DR) in the general population with diabetes. The relationship between obesity and DR...
View ArticleThe role of NAD-dependent deacetylase sirtuin-2 in liver metabolic stress...
NAD-dependent deacetylase Sirt2 is involved in mammalian metabolic activities, matching energy demand with energy production and expenditure, and is relevant to a variety of metabolic diseases. Here,...
View ArticleImpacts of asymmetric hip rotation angle on gait biomechanics in patients...
Knee Osteoarthritis (OA) is a highly prevalent age-related disease. The altered kinematic pattern of the knee joint as well as the adjacent joints affects to progression of knee OA. However, there is a...
View ArticlePostoperative evaluation of special needs and healthy patients with...
This retrospective clinical study was undertaken to comparatively evaluate the number of restorative treatments, endodontic treatments, and tooth extractions performed for patients under general...
View ArticleTreatment and genetic analysis of multiple supernumerary and impacted teeth...
Multiple supernumerary teeth, combined with numerous impacted teeth, can lead to various malocclusions, posing significant treatment challenges. While certain genes associated with syndromic cases of...
View ArticleEffectiveness of post-COVID-19 primary care attendance in improving survival...
Older individuals with multimorbidity are at an elevated risk of infection and complications from COVID-19. Effectiveness of post-COVID-19 interventions or care models in reducing subsequent adverse...
View ArticleImpact of secondhand smoke on air quality in partially enclosed outdoor...
Smoking is a leading cause of premature mortality and morbidity globally. The pollutants generated from smoke are not only harmful to smokers, but also to those exposed to secondhand smoke. As a result...
View ArticleRisk of neuropsychiatric disorders in primary hyperparathyroidism:...
Neuropsychiatric disorders frequently manifest in primary hyperparathyroidism (PHPT), yet evidence of parathyroidectomy’s benefit remains mixed. We sought to compare the incidence of neuropsychiatric...
View ArticleMultivariate associations between neuroanatomy and cognition in unmedicated...
Previous studies that focused on univariate correlations between neuroanatomy and cognition in schizophrenia identified some inconsistent findings. Moreover, antipsychotic medication may impact the...
View ArticleAssociation between organophosphorus insecticides exposure and osteoarthritis...
Organic phosphorus insecticides (OPPs) are a class of environmental pollutants widely used worldwide with potential human health risks. We aimed to assess the association between exposure to OPPs and...
View ArticleHemostasis and complement in allogeneic hematopoietic stem cell...
Hematopoietic stem cell transplantation (HCT) represents a curative treatment option for certain malignant and nonmalignant hematological diseases. Conditioning regimens before HCT, the development of...
View ArticleUse of thermographic imaging for the evaluation of erectile dysfunction and...
Thermographic imaging is a technique to measure infrared radiation to report temperature and has been used in prior research to assess sexual arousal by measuring genital temperature. We hypothesized...
View ArticleOptimization of ESCC Organ Preservation Strategies Based on Chemotherapy
The following is a summary of “Optimizing Organ Preservation Strategies through Chemotherapy-Based Selection in Esophageal Squamous Cell Carcinoma: Results from the CROC Multi-Institutional Phase II...
View ArticleTargeted Palliative Care Enhances Outcomes in Advanced Cancer
In a recent study of supportive care for advanced cancer management, targeted palliative care optimized patient care and enhanced clinical outcomes. Managing symptoms in patients with advanced cancer...
View ArticleMolecular Testing Appears To Be Increasing in eNSCLC
An increasing number of patients with eNSCLC currently have access to biomarker testing and targeted therapies, according to the MYLUNG consortium. Biomarker testing and targeted therapies appear to be...
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