Menin Inhibitors on the Rise in KMT2Ar Acute Leukemia
Revumenib continued to display promising anti-tumor activity in an updated analysis of the phase 2 AUGMENT-101 study among patients with relapsed or refractory KMT2A-rearranged (KMT2Ar) acute leukemia....
View ArticleLUNA 3: Rilzabrutinib Meets Primary Endpoint in ITP
In the phase 3 LUNA 3 trial, rilzabrutinib, compared with placebo, improved efficacy and QOL outcomes with an accompanying favorable safety profile among heavily pre-treated adult patients with immune...
View ArticleImpact of ED and TD in Patients With TC
The following is a summary of “Incidence of Erectile Dysfunction and Testosterone Deficiency in Testicular Cancer Survivors,” published in the January 2025 issue of Urology by Pandit et al....
View ArticleQFR Overestimation of Intermediate Lesions in Donor Vessels Post-CTO
The following is a summary of “Quantitative flow ratio of the donor coronary artery supplying a chronic total occlusion territory,” published in the December 2024 issue of Cardiology by Elbasha et al....
View ArticleSurgeons’ Experience with Musculoskeletal Disorders and Ergonomic Device Use
The following is a summary of “Musculoskeletal Disorders Among Surgeons and Attitudes Towards Wearable Devices for Ergonomic Optimization,” published in the December 2024 issue of Surgery by LaMonica...
View ArticleInfluence of Early Life Factors on Skin Microbiome and AD Development
The following is a summary of “Skin Microbiome in the First Year of Life and Its Association With Atopic Dermatitis,” published in the December 2024 issue of Pediatrics by Rapin et al. The skin...
View ArticleContralateral Amygdala Hypertrophy in Unilateral mTLE With Hippocampal Sclerosis
The following is a summary of “Brain Hypertrophy in Patients With Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis and Its Clinical Correlates,” published in the December 2024 issue of...
View ArticleAortic Root Diameters and Workload in Athletes With eBPR and Normal SBP
The following is a summary of “Association of aortic root diameter and vascular function with an exaggerated blood pressure response to exercise among elite athletes,” published in the December 2024...
View ArticleSerum Relaxin-2 Patterns and Impact of Conception Method on Twins
The following is a summary of “Relationship between relaxin-2 levels in serum and mode of conception in twin gestations: A prospective cohort study,” published in the December 2024 issue of Obstetrics...
View ArticleSex-Specific Effects of MTNR1B rs724030 on Glycemic Traits and WHR
The following is a summary of “MTNR1B Rs724030 Variant is Associated With Islet Function and Women Waist-to-Hip Ratio (WHR) in Healthy Subjects,” published in the December 2024 issue of Endocrinology...
View ArticleRectal Microinflammation and CLDN2 Upregulation in Remission Ulcerative Colitis
The following is a summary of “Importance of rectal over colon status in ulcerative colitis remission: the role of microinflammation and mucosal barrier dysfunction in relapse,” published in the...
View ArticleRadiotherapy vs Endocrine Therapy in Older Women With Low-Risk Early Breast...
The following is a summary of “Single-modality endocrine therapy versus radiotherapy after breast-conserving surgery in women aged 70 years and older with luminal A-like early breast cancer (EUROPA): a...
View ArticlePlasma Aβ42/Aβ40, p-Tau181, and Neurodegeneration Biomarkers Predict MCI Onset
The following is a summary of “Blood-Based Biomarkers and Risk of Onset of Mild Cognitive Impairment Over the Short and Long Term, randomised trial,” published in the December 2024 issue of Neurology...
View ArticleImproving Gout Care Through a Nurse-Led Protocol in Canada
The following is a summary of “Improving Gout Care in a Canadian Academic Medical Center Through a Multidisciplinary Nurse-Led Protocol,” published in the December 2024 issue of Rheumatology by Audet...
View ArticleNintedanib Safety in Patients With RA-ILD
The following is a summary of “Nintedanib in rheumatoid arthritis related interstitial lung disease: real-world safety profile and risk of side effects and discontinuation,” published in the December...
View ArticleExploring the Causal Link Between Frailty and Mental Disorders
The following is a summary of “Causal relationship between genetically predicted mental disorders and frailty: a bidirectional and multivariable mendelian randomization study,” published in the...
View ArticleLong Term Outcomes of Tapered Treatment for Prescription Narcotic Use
The following is a summary of “A prospective cohort of treatment-seeking patients with problematic use of prescription narcotic drugs: study protocol and baseline characteristics,” published in the...
View ArticleDepression Linked to Serum PSA in US Men
The following is a summary of “A cross-sectional study of the association between depression and serum prostate-specific antigen (PSA) among U.S. males: national health and nutrition examination survey...
View ArticleOptimizing KOA Treatment Pathways in Slovenia
The following is a summary of “A mixed-methods study of patient and healthcare professional perceptions of care pathways for knee osteoarthritis,” published in the December 2024 issue of Primary Care...
View ArticleEnhancing Mental and Behavioral Health Training for Family Medicine Residents
The following is a summary of “Evaluation of enhanced mental and behavioral health training for family medicine residents: a research protocol,” published in the December 2024 issue of Primary Care by...
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