Tolebrutinib Slows Disability Worsening in Relapsing MS
In the GEMINI 1 and 2 studies, tolebrutinib did not reach the primary endpoint of reduced annualized relapse rates in relapsing MS compared with teriflunomide. The studies showed a positive result on a...
View ArticleHigh-Dose Simvastatin Does Not Slow Disability Progression in SPMS
The highly anticipated primary results of the phase 3 MS-STAT2 trial failed to show that high-dose simvastatin slows disability progression in secondary progressive MS (SPMS). Simvastatin treatment was...
View ArticleEncouraging Real-World Results of AHSCT to Treat Aggressive MS
In a large-scale real-world cohort, autologous hematopoietic stem cell transplantation (AHSCT) appeared to be effective and beneficial for patients with severe forms of MS. AHSCT led to overall durable...
View ArticleB-Cell-Tailored Dosing of Ocrelizumab Yields Encouraging Results
In a randomized-controlled trial, B-cell-tailored dosing of ocrelizumab yielded encouraging results thus far. Results of an interim analysis of the BLOOMS trial showed very little radiological or...
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Year in Review – Endometrial Cancer
2024 Year in Review: Therapeutics, Diagnostics, and Deep Learning Models Endometrial Cancer Endometrial Cancer New FDA Approval Dostarlimab-gxly (Jemperli) On August 1, 2024, the FDA approved...
View ArticleGut Microbiota Modulates Inflammation & Cortical Damage
To assess the role of gut microbiota as a risk factor of MS, researchers correlated the presence of specific bacteria with 7T MRI metrics. Detrimental bacteria, notably Alistipes onderdonkii, had a...
View ArticleAddressing Stigma Alone May Not Improve PrEP Use in Black MSM
In a study of PrEP use in Black sexual minority men, PrEP stigma was associated with a lower likelihood of current PrEP use in all models examined. PrEP stigma was associated with more than a 2-fold...
View ArticleLeveraging Nonverbal Cues to Build Trust & Improve Patient Care
On a recent episode of PeerPOV: The Pulse on Medicine, Bradley Block, MD, shared how clinicians can use subtle nonverbal cues to convey interest and authority to their patients, which can help build...
View ArticleDepression Management “Crucial” for T2D Care
Research on depression and T2D showed depression impaired adherence to diabetes care, highlighting the need for integrated models addressing both conditions. Research indicates that depression...
View ArticleThe Importance of Screening for Loneliness in COPD & Asthma
Loneliness is a key risk factor for symptom exacerbations and hospitalizations in people with COPD, highlighting the need for targeted interventions. Loneliness appears to be a more important risk...
View ArticlePerformance assessment of preoperative risk assessment tools for elective...
1. In this scoping review of preoperative risk assessment tools for elective noncardiac surgery, cardiopulmonary exercise testing (CPET) was the most assessed tool, particularly with regard to...
View ArticleInavolisib-Based Therapy in PIK3CA-Mutated Advanced Breast Cancer
1. The median progression-free survival was 15.0 months in the inavolisib and 7.3 months in the placebo group, with HR 0.43 (significant). 2. Grade 3-4 adverse events were reported in 88.3% of the...
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#VisualAbstract: Three Cycles of Chemotherapy was Noninfererior to Six Cycles...
Click here to read this study in JAMA. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about...
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#VisualAbstract: Total Hip Replacement Improved Pain and Function versus...
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about...
View ArticleComorbidities in Patients With Psoriasis: A Recap of Recent Research
Research presented at the Fall Clinical Dermatology 2024 and published in the literature highlights the extensive impact of comorbidities in psoriasis. The Fall Clinical Dermatology Conference 2024...
View ArticleReducing In-Home Smoking: Practical Approaches for Primary Care Clinicians
Clinicians can use strategies to reduce in-home smoking, including coaching sessions, educating patients about indoor pollutants, and reinforcing behavioral change. In-home smoking continues to pose...
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Virtual Yoga Classes Aid Chronic Low Back Pain
TUESDAY, Nov. 12, 2024 (HealthDay News) — Virtual yoga classes may be a feasible, safe, and effective treatment option for chronic low back pain (CLBP), according to a study published online Nov. 1 in...
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FDA Approves Emrosi for Rosacea in Adults
TUESDAY, Nov. 12, 2024 (HealthDay News) — The U.S. Food and Drug Administration has approved Emrosi (minocycline hydrochloride) for the treatment of inflammatory rosacea in adults. The extended-release...
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Transitioning to E-Cigarettes Aids Resolution of Respiratory Symptoms
TUESDAY, Nov. 12, 2024 (HealthDay News) — Transitioning from cigarettes to electronic cigarettes (e-cigarettes) is associated with resolution of respiratory symptoms, but the rate of resolution is...
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Topical Human Platelet Extract Noninferior for Photoaging of Hands
TUESDAY, Nov. 12, 2024 (HealthDay News) — Topical human platelet extract (HPE) performs as well as topical vitamin C for skin rejuvenation of dorsal hands, according to a study published in the...
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