Endosomal Trafficking Bypassed by the RAB5B-CD109 Interplay Promotes...
Perineural invasion (PNI) represents a unique biological feature associated with poor prognosis in pancreatic ductal adenocarcinoma (PDAC), especially in the presence of KRAS mutations. Extracellular...
View ArticleActivation of the Influenza B M2 Proton Channel (BM2).
Influenza B viruses have cocirculated during most seasonal flu epidemics and can cause significant human morbidity and mortality due to their rapid mutation, emerging drug resistance, and severe impact...
View ArticleThe ABCs of post-preeclampsia outpatient nephrology care: the Le Mans strategy.
Preeclampsia and hypertensive disorders of pregnancy complicate 3 to 5% of all pregnancies. Chronic kidney disease (CKD), at any stage, reportedly affects 3% of women in childbearing age but most of...
View ArticleUric acid mediates kidney tubular inflammation through the LDHA/ROS/NLRP3...
Hyperuricemia (HUA) is an important factor leading to chronic kidney disease (CKD). The kidney tubular inflammatory response is activated in HUA. This study aimed to investigate whether lactate...
View ArticleA Systematic Literature Review of Modelling Approaches to Evaluate the Cost...
This systematic literature review addresses model-based cost-effectiveness studies for therapy response monitoring with positron emission tomography (PET) generally combined with low-dose computed...
View ArticleExploring the communication access and participation of a young adult with...
This study aimed to describe the nature of interactions between health care professionals and a young adult with autism spectrum disorder with limited speech during an inpatient stay. An observational...
View ArticleRenal injury in NSAIDs: a real-world analysis based on the FAERS database.
This study aims to evaluate the reporting risk of renal injury associated with non-steroidal anti-inflammatory drugs (NSAIDs), with a particular focus on the reporting risk levels and onset times of...
View ArticleFear of the Cancer Coming Back: A Metasynthesis of Fear of Recurrence in...
This review aimed to consolidate existing knowledge on this phenomenon by incorporating direct testimonies from individuals who have experienced breast cancer.A thorough metasynthesis of qualitative...
View ArticleTargeting the SPC25/RIOK1/MYH9 Axis to Overcome Tumor Stemness and Platinum...
In epithelial ovarian cancer (EOC), platinum resistance, potentially mediated by cancer stem cells (CSCs), often leads to relapse and treatment failure. Here, the role of spindle pole body component 25...
View ArticleKnowledge of pelvic floor muscles in community-dwelling women aged over 60:...
To investigate the awareness of the pelvic floor muscles (PFMs) and PFM exercises (PFME) knowledge, training and experience in community-dwelling women aged 60 and over and its relationship with...
View ArticleCurrent and Novel Therapies for Cluster Headache: A Narrative Review.
Cluster headache (CH) is an excruciating and debilitating primary headache disorder. The prevalence is up to 1.3%, and the typical onset is around age 30. Often misdiagnosed as migraine, particularly...
View ArticleA Digital Health Behavior Intervention to Prevent Childhood Obesity: The...
Infant growth predicts long-term obesity and cardiovascular disease. Previous interventions designed to prevent obesity in the first 2 years of life have been largely unsuccessful. Obesity prevalence...
View ArticleModel Predicts Lymph Node Metastasis in EC
A machine-learning model that combines multisequence magnetic resonance imaging radiomics with clinical parameters predicted lymph node metastasis (LNM) in patients with type I endometrial cancer (EC),...
View ArticlePanel Shows High Sensitivity in MMR Testing for EC
An MSH6-PMS2 combination panel may be a reliable, cost-effective alternative to the conventional, four-protein MSH2-MSH6-MLH1-PMS2 panel for mismatch repair (MMR) immunohistochemistry testing in...
View ArticleAMD Linked to Higher RA Risk
Age-related macular degeneration (AMD) is associated with a higher risk for rheumatoid arthritis (RA), according to a study published in Scientific Reports. A research team from South Korea examined...
View ArticleRA Associated With Significant Economic & Human Burdens
Rheumatoid arthritis (RA) is associated with higher healthcare expenditures and suboptimal QOL in US adults, according to a study published in ACR Open Rheumatology. Yinan Huang, PhD, from the...
View ArticlePsoriasis, Other Comorbidities Impact Development of Latent Autoimmune...
Patients with autoimmune diseases, including psoriasis, are at higher risk for being diagnosed with latent autoimmune diabetes in adults, or LADA. At the Fall Clinical Dermatology Conference 2024,...
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Patients Living Outside Metropolitan Statistical Areas Travel Farther for...
MONDAY, Nov. 4, 2024 (HealthDay News) — In a research letter published online Nov. 5 in the Annals of Internal Medicine, nationally representative measures of patient travel patterns are presented....
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Policies About Late-Career Physicians Are Considered Successful
MONDAY, Nov. 4, 2024 (HealthDay News) — Institutional leaders consider policies about late-career physicians (LCPs; physicians working beyond age 65 to 75 years) to be successful, according to a study...
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Improvement Seen in Some Features of PCOS With Weight Loss Interventions
MONDAY, Nov. 4, 2024 (HealthDay News) — Weight loss interventions are associated with improvement in some features of polycystic ovary syndrome (PCOS), according to a study published online Nov. 5 in...
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