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Characterizing Antibody Responses in Invasive Strep a SDSE and GBS Infections

The following is a summary of “Serological responses to target Streptococcus pyogenes vaccine antigens in patients with proven invasive beta-haemolytic streptococcal infections,” published in the...

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Symptom Clusters Offer Insight Into COPD Clinical Complexity

A recent study found that the respiratory and non-respiratory symptom burden in patients with COPD is high when compared with patients without COPD. The respiratory and nonrespiratory symptom burden in...

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LOXL2 Identified as Therapeutic Target in PMF

A study that investigated the role of lysyl oxidase like-2 (LOXL2) in primary myelofibrosis (PMF) showed significantly higher LOXL2 expression in PMF, as well as worse disease outcomes and increased...

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Low-Risk Myelofibrosis Shows Evidence of Disease Progression

About 60% of patients with low-risk myelofibrosis showed evidence of progression during more than 4 years of follow-up, according to findings published in Clinical Lymphoma Myeloma and Leukemia....

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Non-Medical Barriers to LDLT Persist at Multiple Levels

Socioeconomic disparities, information gaps, and inadequate institution support are among the non-medical barriers hindering wider adoption of living donor liver transplantation (LDLT), according to...

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Composite Biomarker Could Reduce Need for Biopsies

A composite biomarker approach that uses multiparametric MRI (mpMRI) and serum liver tests could enhance monitoring of liver grafts and reduce the need for biopsies in patients with a liver transplant,...

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HIV Stigma Indirectly Impacts Viral Non-Suppression

Internalized HIV stigma has an indirect impact on viral non-suppression through several factors, according to findings published in AIDS. Timothy Crawford, PhD, MPH, and colleagues assessed the...

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Brief Intervention Reduces Alcohol Use in Men With HIV

A brief intervention consisting of two sessions can provide significant decreases in alcohol use among sexual minority men (SMM) with HIV, with 1 month of interactive text messaging yielding greater...

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The association between serum S100β levels and prognosis in acute stroke...

1. S100β levels 24 hours after IVT were independently associated with HT, infarct volume, and prognosis in stroke patients Evidence Rating Level: 2 (Good) Intravenous thrombolysis (IVT) is the...

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Pomalidomide effective in reducing epistaxis in hereditary hemorrhagic...

1. Among patients with hereditary hemorrhagic telangiectasia (HHT), pomalidomide significantly reduced the severity of epistaxis and improved quality of life. 2. Pomalidomide was associated with...

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Ziresovir reduces the severity of respiratory syncytial virus in hospitalized...

1. Ziresovir, an antiviral drug targeted at respiratory syncytial virus (RSV), was superior to placebo in reducing signs and symptoms of hospitalized young children with RSV infection. 2. The incidence...

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Combination of doxorubicin-trabectedin with trabectedin improves...

1. In patients with advanced leiomyosarcoma, a regimen of doxorubicin-trabectedin was superior to doxorubicin alone in improving progression-free and overall survival. 2. Trabectedin was associated...

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#VisualAbstract: Extended Lymphadenectomy is Not Associated with Improved...

Click here to read this study in NEJM.  ©2024 2 Minute Medicine, Inc. All rights reserved. No works may be reproduced without expressed written consent from 2 Minute Medicine, Inc. Inquire about...

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Using the DemRisk prediction model to indentify individuals at high risk for...

1. Predicting dementia in primary care settings for a 60-79 year old cohort should include age, history of stroke or epilepsy, gait problems, anticholinergic burden, use of SSRIs, receipt of social...

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Effectiveness of LI-ESWT for Reducing Plaques and Pain in PD

The following is a summary of “Low-intensity extracorporeal shock wave therapy for Peyroniès disease: a systematic review and meta-analysis,” published in the October 2024 issue of Urology by Li et al....

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Impact of Aldosterone on Multiple Organ Damage in Hypertensive Emergency

The following is a summary of “Role of aldosterone in various target organ damage in patients with hypertensive emergency: a cross-sectional study,” published in the October 2024 issue of Nephrology by...

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Self-Care Education Reduces Nausea After SCT for Leukemia

A mobile app offering treatment and self-care information reduced nausea and vomiting in patients who underwent stem cell transplantation for leukemia. Self-care education via a smartphone app...

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Strategies That Improve Physical Activity in Patients With Stable COPD

Researchers identified intervention components that could reduce sedentary behavior and increase physical activity in patients with moderate, stable COPD. Goal setting, verbal education,...

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Muscle Mass Linked to AML/MDS Outcomes

Maintaining muscle mass was associated with better physical and clinical outcomes in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS), according to a study published in the...

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Definition and Mechanisms of Exercise-Induced Heat Sensitivity in pwMS

The following is a summary of “Exercise-induced heat sensitivity in patients with multiple sclerosis: Definition, prevalence, etiology, and management—A scoping review,” published in the October 2024...

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