A Failed Skin Graft
Click on the image to enlarge Poll Patient Case A patient in her mid-20s sustained full-thickness burns over 80% of her body after sleeping during a house fire, which resulted in a 60% mortality...
View ArticleThe Latest in Endometrial Cancer: Liquid Profiling, LVSI, and More
Recent research into endometrial cancer has explored minimally invasive versus open surgical approaches, liquid profiling, recurrence prediction, and more. This year, a wealth of research into...
View ArticleRevised McDonald Criteria Allows Earlier & More Precise MS Diagnosis
The revised McDonald criteria allow the diagnosis of MS in certain cases in asymptomatic people who have had a radiologically isolated syndrome (RIS). Dissemination in time (DIT) should no longer be...
View ArticleBlood Markers Predict MS Progression
Change in serum glial fibrillary acidic protein (sGFAP) during the first 2 years of treatment predicted future risk for progression independent of relapse activity (PIRA) in two independent MS cohorts....
View ArticleHigh Depression Genetic Burden Associated With MS Disease Activity
In a Canadian study, a higher depression genetic burden was associated with increased MS disease activity. The findings exclude reverse causality as a reason for worse outcomes in people with...
View ArticleTh1/Th17 CD4+ T Cells Predict Vedolizumab Efficacy in IBD
The following is a summary of “Multimodal profiling of peripheral blood identifies proliferating circulating effector CD4+T cells as predictors for response to integrin α4β7-blocking therapy in...
View ArticleEfficacy of POS in Healthy Subjects for Reversing Mydriasis
The following is a summary of “Reversal of Pharmacologically Induced Mydriasis with Phentolamine Ophthalmic Solution,” published in the September 2024 issue of Ophthalmology by Pepose et al....
View ArticleIL-17 Inhibitors Increase Fungal Infection Risk in Patients With Psoriasis,...
The following is a summary of “Risk of fungal infection in patients with psoriasis receiving biologics: a retrospective single-center cohort study,” published in the September 2024 issue of Dermatology...
View ArticleEfficacy of Fazirsiran in AAT Deficiency Liver Disease
The following is a summary of “Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA),” published in the October 2024 issue of...
View ArticleGenetic Variation at HERC2 SNP Linked to UM Survival
The following is a summary of “Survival in uveal melanoma patients is linked to genetic variation at HERC2 SNP rs12913832,” published in the September 2024 issue of Ophthalmology by Gelmi et al. Uveal...
View ArticleComparing Nicardipine and Clevidipine for Hypertensive Crisis Control
The following is a summary of “Evaluation of the Efficacy and Safety of Nicardipine Versus Clevidipine for Blood Pressure Control in Hypertensive Crisis,” published in the October 2024 issue of...
View ArticleLong-Lasting Epigenetic Alterations in Neurosyphilis After Treatment
The following is a summary of “Epigenetic Changes in Cerebrospinal Fluid and Blood of People with Neurosyphilis,” published in the October 2024 issue of Infectious Diseases by Mostaghimi et al....
View ArticlePhenotypic Analysis of Acute Respiratory Failure Among Patients in ICU with...
The following is a summary of “Derivation and validation of generalized sepsis-induced acute respiratory failure phenotypes among critically ill patients: a retrospective study,” published in the...
View ArticleAssessing Itch in Plaque Psoriasis: The Latest Tools & Questionnaires
Dermatologists recently have developed and validated several tools for assessing itch in plaque psoriasis, such as the Peak Pruritus-Numerical Rating Scale. Historically, psoriasis has been considered...
View ArticleBrain Mechanisms Supporting Empathy During Pain Perception
The following is a summary of “I feel your pain: higher empathy is associated with higher posterior default mode network activity,” published in the October and 2024 issue of Pain by Oliva et al....
View ArticleNTM Pulmonary Disease Incidence & Prevalence Increasing Among Adults 65 Years...
The following is a summary of “Nontuberculous mycobacterial pulmonary disease (NTM PD) incidence trends in the United States, 2010–2019,” published in the October 2024 issue of Infectious Diseases by...
View ArticleFocal Inflammation Low After OCR Discontinuation in Patients with RRMS
The following is a summary of “Recurrence of disease activity after ocrelizumab discontinuation in multiple sclerosis,” published in the September 2024 issue of Neurology by Coerver et al....
View ArticleAdaptive Humor Skills Reduce Depression and FoP in pwMS
The following is a summary of “Exploring humor as a coping factor against depressive mood and fear of progression in people with multiple sclerosis with moderate disability: A cross-sectional analysis...
View ArticleEculizumab Effectiveness in NMOSD and Risks of Postvaccination Attacks and...
The following is a summary of “Eculizumab Use in Neuromyelitis Optica Spectrum Disorders: Routine Clinical Care Data from a European Cohort,” published in the October 2024 issue of Neurology by...
View ArticleTips for Being an Effective Leader of the Healthcare Team
Linda Girgis, MD, FAAFP, provides expert advice on how to be an effective leader of a healthcare team, and reminds physicians that leading well takes practice. Whether or not we want to be, we are...
View Article