A prospective trial published in the International Journal of Nursing Studies demonstrated that a low-speed, continuous infusion technique effectively reduced central venous catheter (CVC) occlusion. Lead authors Mian Zhou, Shan Dong, and colleagues conducted a randomized, controlled study to investigate the effectiveness of the low-speed continuous infusion catheter technique compared with routine care for maintaining CVC patency. They enrolled 251 patients from 14 medical institutions, 125 in the intervention group and 126 in the control group. The primary outcome, catheter occlusion rate, was significantly lower in the intervention group at 3 and 7 days compared with the control group. Additionally, nurse satisfaction was significantly higher in the intervention group (115/125 [92%]; 95% CI, 0.858-0.961) than in the control group (104/126 [82.54%]; 95 % CI, 0.748-0.887) (χ2=5.049; P=0.025). There were no significant differences in complication rates. Zhou, Dong, and colleagues concluded that the low-speed, continuous infusion catheter technique effectively maintained CVC patency, improved nurse satisfaction, and ensured a high safety level.
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