The following is a summary of “Patient preferences for treatment of Bowen’s disease,” published in the December 2024 issue of Dermatology by Ahmady et al.
Discrete choice experiments (DCEs) are increasingly utilized to analyze and quantify patient preferences for treatments, services, or screening by examining the decisions among different alternatives.
Researchers conducted a retrospective study to examine patient preferences for the treatment of Bowen’s disease using DCEs.
They utilized a DCE alongside a randomized controlled non-inferiority trial comparing the effectiveness of surgical excision, MAL-PDT, and 5-fluorouracil cream for treating Bowen’s disease. Preferences were assessed by presenting patients with choice tasks involving these treatments, considering attributes such as effectiveness, cosmetic outcome, side effects, treatment duration, and process. A mixed logit model was applied to handle the panel data (repeated choices for each respondent) and account for preference heterogeneity
The results showed 215 patients completed the DCE. Patients preferred surgical excision, with non-invasive therapies being less favored, as reflected by a significant negative label effect. Moderate and good to excellent cosmetic outcomes were preferred over poor cosmetic outcomes for all treatments. Additionally, mild to moderate side effects were considered acceptable and preferred over severe side effects.
Investigators concluded that it was crucial to discuss patient preferences regarding treatment options (surgical excision, 5-fluorouracil cream, MAL-PDT) considering factors such as effectiveness, cosmetic outcomes, and side effects, given the observed patient preference for surgical excision and 5-fluorouracil cream over MAL-PDT.
Source: academic.oup.com/bjd/advance-article-abstract/doi/10.1093/bjd/ljae477/7919384
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