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Examining the Association Between Cognitive Function and CR for Mood Disorders

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The following is a summary of “Cognitive reserve and cognition in mood disorders: a systematic review and meta-analysis,” published in the July 2024 issue of Psychiatry by Camprodon-Boadas et al.


Individuals with mood disorders display considerable variability in cognitive functioning, and cognitive reserve (CR) has been associated with numerous positive outcomes, such as patients with enhanced cognitive performance.

Researchers conducted a retrospective study analyzing the relationship between CR and cognitive functioning in mood disorders, including bipolar and depressive disorders.

They examined original CR and cognitive performance research in adults with mood disorders adhering to PRISMA guidelines. Literature searches were performed in Scopus, PubMed, and Web of Science from 2002 to September 2023. The Newcastle-Ottawa Scale (NOS) was used for quality assessment. Seventeen studies met the inclusion criteria for the review, and 11 were included in the meta-analysis.

The result showed that qualitative and quantitative analyses demonstrated a positive relationship between CR measures and cognitive domains, suggesting CR as a protective factor for cognitive functioning in adults with mood disorders.

Investigators concluded that enhancing CR could improve cognitive outcomes in individuals with mood disorders, highlighting the potential benefits of CR in mitigating cognitive impairments associated with the conditions.

Source: sciencedirect.com/science/article/abs/pii/S0165178124003688

The post Examining the Association Between Cognitive Function and CR for Mood Disorders first appeared on Physician's Weekly.


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